BulkSupplements Creatine Monohydrate is a micronized creatine monohydrate powder, 5 g per serving, that the seller says supports muscle strength, endurance and recovery. Creatine monohydrate is a common dietary ingredient with a substantial body of human research, and the safety reviews in that research generally find side effects uncommon and creatine well tolerated in short-term studies. The 2007 safety review lists skeletal muscle, kidney and gastrointestinal effects as isolated reports.
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Quick safety summary
If you searched for bulk supplements creatine monohydrate, this is the same product. Here is the short version before the details.
Safety summary
- What is in it: creatine monohydrate, 5 g per serving (2 tsp, about 5 grams). The label lists Other Ingredients as None and Allergens as None.
- Reported effects: the 2007 safety review lists isolated reports involving the gastrointestinal tract, and most clinical studies it covers did not find more side effects with creatine. Kidney and muscle effects also appear only as isolated reports in that review.
- Medicines to ask about: ask your pharmacist to check your full medicine list before you start. The interaction the research discusses is with caffeine, which a 2015 review covers alongside creatine.
- Ask a clinician first: if you are pregnant or nursing, under 18, live with a medical condition (including kidney problems), take any medicine, or have surgery scheduled.
What is BulkSupplements Creatine Monohydrate?
The product page lists it as Creatine Monohydrate (Micronized) Powder, SKU CM500, unflavored. The seller says each serving ‘contains 100% premium-grade creatine monohydrate.’ The label lists one ingredient:
| Ingredient | Amount per serving (as printed) |
|---|---|
| Creatine Monohydrate | 5g |
The label gives a serving size of 2 tsp (about 5 grams), 100 servings per container, and Daily Value ‘not established.’ It lists Other Ingredients as None and Allergens as None. The label also carries gluten free, soy free, dairy free, no added sugar and additive free claims. The seller’s graphics also show a capsule version: 5,000 mg per serving, 210 capsules, 30 servings.
Why people use creatine monohydrate
The seller says creatine is ‘known to enhance muscle strength and endurance, improve exercise recovery, and accelerate lean muscle mass development.’ It also says creatine is ‘known for its role in ATP production,’ and that it ‘plays a role in brain energy metabolism, which may support focus and mental clarity.’ Those are the maker’s statements.
The strength findings in the research come from exercise studies. A 2015 review of creatine and caffeine reports consistent improvements in strength and power for exercise bouts of 30 seconds or less at high intensity.
The brain research is newer. A 2023 randomised trial describes creatine as a compound that helps recycle adenosine triphosphate (ATP), the body’s energy molecule, in muscle and brain tissue, and notes that supplementation raises brain creatine levels. Its results are covered below. For a fuller walk through the human studies, see Creatine Benefits: Human Studies, Side Effects and Safety (our research library).
What the research says about creatine side effects
These studies looked at creatine supplements in general, not at this brand or this powder. Read them as evidence about the ingredient.
| Study | What it looked at | What it reported on side effects |
|---|---|---|
| 2007 safety review | Clinical studies of creatine in healthy volunteers and patient groups | Well tolerated by most people in short-term studies. Isolated reports suggest effects on muscle, kidney and the gastrointestinal tract. Most clinical studies did not find an increased incidence of side effects, and no clinically significant changes in kidney, liver, heart or muscle function. Few data on long-term use. |
| 2019 renal function meta-analysis | 290 studies screened; 15 in the qualitative and 6 in the quantitative analysis | The reported statistics show a creatinine difference (SMD 0.48, P=.001) and a urea difference (SMD 1.10, P=.004). The authors concluded creatine does not induce renal damage in the studied amounts and durations. |
| 2023 cognitive trial | 123 participants; cross-over, double-blind, placebo-controlled; 5 g daily for 6 weeks per period | Side effects were reported significantly more often for creatine than for placebo (p = 0.002, RR = 4.25). |
| 2015 creatine and caffeine review | Concurrent creatine and caffeine use in high-intensity exercise | Caffeine may blunt creatine’s performance effect. The authors suggest gastrointestinal side effects from taking both together could play a part, and consider a pharmacokinetic interaction unlikely. |
Most of the research describes side effects as uncommon. The 2023 trial found side effects were reported significantly more often on creatine than on placebo (RR 4.25). The trial did not specify what those side effects were. Its authors say larger studies are needed to confirm or rule out its cognitive findings.
Common side effects and what to do about them
The research mentions stomach and gut complaints. The 2007 review lists the gastrointestinal tract among the areas with isolated reports, and the 2015 review of creatine and caffeine names gastrointestinal side effects from taking both together as a possible explanation for caffeine blunting creatine’s performance effect. The product page gives its own instruction: ‘If you experience any adverse effects, discontinue use and consult your healthcare provider.’
If stomach upset keeps going, stop and talk with a clinician or pharmacist. If you notice a change you did not expect, bring it to a clinician and mention the creatine.
Does creatine increase creatinine?
A 2019 systematic review and meta-analysis set out to test concerns that creatine could overwhelm liver and kidney function. It screened 290 studies, included 15 in its qualitative analysis and 6 in its quantitative analysis, and its authors concluded that creatine does not induce renal damage in the studied amounts and durations. Its reported statistics do show a creatinine difference (SMD 0.48, 95% CI 0.24-0.73, P=.001), so mention creatine to your clinician before any kidney test.
The 2007 review notes few data on long-term consequences, so if you plan long-term use, ask a clinician about it. If you have a kidney test coming up, tell your clinician you take creatine before the test.
Medicines and other products to ask about
The 2015 review of creatine and caffeine reports research suggesting caffeine may blunt creatine’s performance effect. Its authors consider a pharmacokinetic interaction unlikely, but suggest gastrointestinal side effects from taking the two together may play a part. Keep that in mind if you use coffee or a caffeinated pre-workout alongside creatine.
For any medicine you take, ask your pharmacist to check your full list before you start. The product page also tells people taking medication to consult their healthcare provider.
Who should ask a clinician first
- Pregnant or nursing: the product page says to consult your healthcare provider before using it if you are pregnant or nursing.
- Under 18: the seller’s terms say its products are for adults only.
- A medical condition, including kidney problems: the product page says to consult your provider if you have a medical condition.
- Taking any medicine: ask your pharmacist or clinician first.
- Surgery scheduled: tell the surgical team you take creatine before the procedure.
- Long-term use: the 2007 review notes few long-term data, so plan that conversation with a clinician.
How to start and when to stop
The label serving is 2 tsp, about 5 grams. The 2023 trial used 5 grams daily for 6 weeks in each period. Check the How to Use section on the product page for the seller’s directions, and ask customer service if anything is unclear.
Stop if side effects worry you, and talk with a clinician. That is the same step the seller’s warning gives.
Prices, subscription and how to order
Prices as of October 28, 2026; check the checkout for today’s. You can check today’s price and choose a size on the Product Page.
| Option | Size | Price shown | Calculated cost per 5 g serving* |
|---|---|---|---|
| One-time purchase, powder | 500 g (1.1 lb), 100 servings | $22.97 USD (sale price) | about $0.23 |
| Subscribe and save, delivered monthly | 500 g, 100 servings | $20.67 USD (10% off) | about $0.21 |
*Calculated by dividing the price by the 100 servings the label lists.
The subscription also offers delivery every 2, 3, 4, 5 or 6 months, each with 10% off. The page says subscriptions auto-renew and that you can skip or cancel anytime, with details in its subscription policy. Other sizes are listed on the Product Page: 100 g, 250 g, 1 kg, 5 kg and 25 kg.
The seller says free shipping applies to orders over $59 USD after discounts within the contiguous U.S. only, with 2 day delivery to 99.4% of USA; flat-rate shipping starts at $9.95, and the Terms say 3-5 business days is typical delivery. Before you pay, read the cart: one reviewer on the product page says insurance was added to their order without them choosing it.
Refund and return terms
The seller’s refund policy reads like this:
- Unopened: return within 30 days from the invoice date for a full refund of the original purchase price. Return postage is not refunded, and neither are shipping charges or applied discount codes.
- Opened: return within 30 days from the invoice date for a partial refund equal to the price of the smallest unit the seller offers for that product. Shipping charges and discounts are not refundable. The policy’s example is a 500-gram bag, refunded at the price of the smallest size.
- Returned unaltered: Wholesale quantities are not eligible for the opened-item refund and get no refund for opened items, but wholesale orders returned unaltered receive a full refund, shipping excluded.
- After 30 days: customer service will not investigate order disputes past the 30-day grace period. The policy says its terms are enforced ‘at the discretion of Bulksupplements.com.’
- International orders: the seller is not responsible for customs or import rules, and shipping for a refused or abandoned package is not refunded.
Customer service is available every day from 7:30 AM to 4:00 PM PST by live chat, phone and email. Contact them within the 30 days if something is wrong with your order.
Is BulkSupplements Creatine Monohydrate legit, and how do you check?
The seller, BulkSupplements.com, describes itself as a United States company with fulfillment centers in Las Vegas and Nashville. Its About page is located in Henderson, Nevada, calls the company a trusted supplier, and says each supplement is tested by a third-party laboratory before distribution. The product page carries several ‘#1 Best Seller’ labels, including ‘#1 Best Seller in CREATINE,’ and shows 10,016 reviews in one place and 10,018 in another.
The seller’s About page describes its manufacturing as an ‘NSF Certified and FDA-registered cGMP manufacturing facility.’ A 1994 General Accounting Office report on FDA regulation found that the agency generally oversees dietary supplements case by case, responding to complaints or other information about safety or labeling, and that manufacturers do not submit safety data to FDA before marketing. For the agency’s current information, see the U.S. Food and Drug Administration and its dietary supplements page.
To check for yourself, ask customer service for the third-party test results for the batch you are buying, read the refund terms above, and read your cart before paying.
What the research still leaves open
- Most of the studies are short-term, and the 2007 review notes few data on long-term consequences.
- The 2023 trial’s Bayesian analysis supported a small possible benefit, but neither main test reached significance and the authors say larger studies are needed. The effect bordered significance on one test (p = 0.064) and not on the other (p = 0.327), and the authors say larger studies are needed to confirm or rule out the effect.
- The product page says its statements ‘have not been evaluated by the Food and Drug Administration.’
Pairing creatine with training and daily movement
The strength findings in the 2015 review are for short, high-intensity exercise, so the powder fits best as one part of a training plan. Keep it in a routine with regular strength work and movement breaks, especially if you sit for long periods. If you are returning to training after an injury, rehab done right is a useful read. If you live with joint or muscle discomfort and are comparing other options, pain relief from the inside out covers supplements more broadly. If you also take a pain medicine, potential side effects of pain medications is worth reading.
Before you order
- Check the label serving and the How to Use section on the product page.
- Ask customer service for the third-party test results for the batch you are buying.
- Read the cart for any insurance add-on before you pay.
- Ask your pharmacist about any medicine you take, and talk with a clinician if you are pregnant, nursing, under 18, or have a medical condition.
- Keep your invoice, because the 30-day return window runs from the invoice date.
By The Nerve & Joint Pain Desk Editorial Team